Int. J. Dev. Biol. 41: 245 - 254 (1997)
© UPV/EHU Press

Comparative stem cell biology.

P Hollands

Biomedical Research Centre, Anglia Polytechnic University, Cambridge, United Kingdom. phollands@bridge.anglia.ac.uk

ABSTRACT This review collates data from a range of stem cells studies in an attempt to bring together an overall view of stem cell biology. Data from hemopoietic, keratopoietic, hepatopoietic and neuropoietic stem cells are presented. The developmental and cell biology of each system is discussed in an attempt to develop a comparative view of stem cell biology. Comparisons are drawn in the areas of clonal analysis, surface antigen expression, adhesion molecules and cytokine interactions. Where appropriate the role of embryonic stem (ES) cells is also considered in the developmental biology of the cells in question.