Int. J. Dev. Biol. 40: 719 - 725 (1996)
© UPV/EHU Press

Heart development and regeneration in urodeles.

A W Neff, A E Dent and J B Armstrong

Medical Sciences Program, Indiana University, School of Medicine, Bloomington 47405, USA. neff@indiana.edu

ABSTRACT Classical fate mapping and transplantation studies have yielded a rich embryological understanding of heart development in urodeles. Recent advances in understanding the molecular nature of many early developmental events can be applied to urodele heart development. In this review we examine urodele heart development from both morphological and molecular viewpoints. We focus primarily on cardiac induction, early cardiogenesis, and heart regeneration.