Int. J. Dev. Biol. 37: 111 - 116 (1993)
Special Issue: Developmental Aspects of Neoplasia
Two proto-oncogenes that play dual roles in embryonal cell growth and differentiation
Published: 1 March 1993
Abstract
The function of growth factors in early development is reviewed. Special emphasis is on the epidermal growth factor and its receptor, and on the c-fos and its family of transcriptional factor proteins, which play an important role in modulating the growth and differentiation of early embryos and embryonal carcinoma cells.