Two proto-oncogenes that play dual roles in embryonal cell growth and differentiation.

E D Adamson

doi:10.1387/ijdb.8507557

Linking Development, Stem Cells and Cancer Research

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Two proto-oncogenes that play dual roles in embryonal cell growth and differentiation.

E D Adamson

La Jolla Cancer Research Foundation, CA 92037.

ABSTRACT The function of growth factors in early development is reviewed. Special emphasis is on the epidermal growth factor and its receptor, and on the c-fos and its family of transcriptional factor proteins, which play an important role in modulating the growth and differentiation of early embryos and embryonal carcinoma cells.