Int. J. Dev. Biol. 33: 417 - 438 (1989)

Vol 33, Issue 4

The extracellular matrix and cell surface, mediators of cell interactions in chicken gastrulation

Published: 15 December 1989

F Harrisson

Department of Anatomy and Embryology, State University of Antwerp, Belgium.

Abstract

This article reviews the factors that are involved in cell-cell and cell-matrix interactions during chicken gastrulation. The chemical nature of the extracellular matrix, the structure, composition, cellular origin and remodeling of the basement membrane, and the nature of the cell surfaces are successively analyzed in relation to a variety of cell biological processes, such as cell-to-cell and cell-to-substrate adhesion, specific binding to biological macromolecules and to receptors of the cell surface, promotion of cell migration and positioning, transmembrane triggering of intracellular events, and modulation of cell shape. These processes are the cellular basis of morphogenesis in the chicken blastoderm.