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Int. J. Dev. Biol. 57: 133 - 139 (2013)
doi: 10.1387/ijdb.130031nv
© UPV/EHU Press

Classification, epidemiology and therapies for testicular germ cell tumours

Nikhil Vasdev*, Andrew Moon and Andrew C. Thorpe

Department of Urology, Freeman Hospital, Newcastle upon Tyne, United Kingdom

ABSTRACT Testicular germ cell tumours (TGCT) account for between 1% and 1.5% of male neoplasms and 5% of urological tumours in general. They are classified broadly into Seminoma, which resemble primordial germ cells (PGCs), and Non-Seminoma, which are either undifferentiated (embryonal carcinoma) or differentiated (exhibiting a degree of embryonic (teratoma) or extra-embryonic (yolk sac choriocarcinoma) patterning). We present the current details of the latest classification, epidemiology and treatment aspects of TGCT in the UK in our review.

Keywords:

classification, epidemiology, therapy, testicular germ cell tumor, prognosis

*Corresponding author e-mail: nikhilvasdev@doctors.org.uk