Int. J. Dev. Biol. 43: 773 - 775 (1999)
© UPV/EHU Press

Fate mapping the mouse embryo.

K A Lawson

Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Utrecht. lawson@niob.knaw.nl

ABSTRACT The use of clonal analysis to obtain a fate map of the epiblast of the mouse embryo and to investigate cell distribution during gastrulation and early neurulation is described in a personal reminiscence. A revised fate map of the epiblast at 6.5 days gestation is provided, and the development of 3-dimensional, quantitative image analysis techniques outlined.