Fate mapping the mouse embryo.

K A Lawson

doi:10.1387/ijdb.10668985

Linking Development, Stem Cells and Cancer Research

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Fate mapping the mouse embryo.

K A Lawson

Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Utrecht. lawson@niob.knaw.nl

ABSTRACT The use of clonal analysis to obtain a fate map of the epiblast of the mouse embryo and to investigate cell distribution during gastrulation and early neurulation is described in a personal reminiscence. A revised fate map of the epiblast at 6.5 days gestation is provided, and the development of 3-dimensional, quantitative image analysis techniques outlined.