Int. J. Dev. Biol. 43: 773 - 775 (1999)

Vol 43, Issue 7

Special Issue: The Hubrecht Laboratory

Fate mapping the mouse embryo

Published: 1 October 1993

K A Lawson

Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Utrecht. lawson@niob.knaw.nl

Abstract

The use of clonal analysis to obtain a fate map of the epiblast of the mouse embryo and to investigate cell distribution during gastrulation and early neurulation is described in a personal reminiscence. A revised fate map of the epiblast at 6.5 days gestation is provided, and the development of 3-dimensional, quantitative image analysis techniques outlined.