The International Journal of Developmental Biology

Int. J. Dev. Biol. 50: 369 - 370 (2006)

https://doi.org/10.1387/ijdb.062142sg

Vol 50, Issue 4

In memoriam Lauri Saxén (1927-2005)

Open Access | Published: 1 March 2006

Scott Gilbert

Pennsylvania, USA

Abstract

Dr. Lauri "Tupu" Saxén died last October (2005) at the age of 78. He was a physician, a scientist, a photographer, a naturalist, a great story-teller and a man who enjoyed science enormously. His name has become synonymous with the Finnish school of Developmental Biology, a school that focuses on reciprocal inductive interactions during vertebrate organogenesis. But many biologists probably don't know the full extent of his importance to the field. A few years ago, I had the occasion to outline some of his contributions which are so varied and important that it is difficult to believe that they are the work of one person, and I have included them in this brief eulogy. One could divide his scientific contributions into five categories: (1) the threshold hypothesis of amphibian metamorphosis; (2) the double-gradient hypothesis of primary embryonic induction; (3) the analysis of reciprocal induction during kidney development; (4) the integration of developmental biology with epidemiology and (5) the maintenance of a national infrastructure for science.

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