Int. J. Dev. Biol. 45: S103 - S104 (2001)

Vol 45, Issue S1

Study of novel genes involved in odontoblast and ameloblast differentiation

Published: 1 June 2001

FJ Unda, N Iehara, S De-Vega, M De-La-Fuente, A Vilaxa, Y Yamada

Univ Basque Country, Fac Med & Dent, Dept Cell Biol, E-48940 Leioa, Vizcaya, Spain; Natl Inst Dent & Craniofacial Res, NIH, Bethesda, MD USA; Univ Tarapaca, Dept Biol & Salud, Arica, Chile

Abstract

Teeth are organs which develop by inductive interactions between dental epithelium and subjacent mesenchyme. In order to identify genes involved in odontoblast and ameloblast differentiation, we have constructed a cDNA library from E19.5 mouse molars. In this work, we report partial DNA sequences of 10 non-characterized genes. In addition, we show cell expression of the transcripts in mouse embryo molars by in situ hybridization. We discuss the role of these genes in cell differentiation.