Vol. 63 Nos. 3/4/5 (2019) pp.73-258

Early mammalian development: from basic research to the clinic

Cover legend

Mouse preimplantation embryos at various stages of development immunofluorescently stained for the presence of lineage-specific markers, DNA (blue) and F-actin (green). Top left: 16-cell embryo stained for the presence of F-actin and pERM (yellow). Top right: early blastocyst revealing the location of F-actin and the trophectoderm marker Cdx2 (red). Bottom: late blastocyst fluorescently labeled with the trophectoderm marker Cdx2 (red), the epiblast marker Sox2 (white) and the primitive endoderm marker Sox17 (green). DNA was labeled with Draq5.

Preface

Early mammalian development: from basic research to the clinic
Aneta Suwińska and Anna Ajduk
Int. J. Dev. Biol. (2019) 63: 73-75

Introductory Papers

Breakthroughs and challenges of modern developmental biology and reproductive medicine
Simon Fishel, Anna-Katerina Hadjantonakis, Berenika Plusa, Laura Rienzi, Yojiro Yamanaka, Aneta Suwińskaand Anna Ajduk
Int. J. Dev. Biol. (2019) 63: 77-82
A short history of in vitro fertilization (IVF)
Martin H. Johnson
Int. J. Dev. Biol. (2019) 63: 83-92

Reviews

Mitochondria and lipid metabolism in mammalian oocytes and early embryos
Josephine Bradley and Karl Swann
Int. J. Dev. Biol. (2019) 63: 93-103
Function of atypical mammalian oocyte/zygote nucleoli and its implications for reproductive biology and medicine
Josef Fulka, Jr., Michal Benc, Pasqualino Loi, Alena Langerovaand Helena Fulka
Int. J. Dev. Biol. (2019) 63: 105-112
Regulation of the cell cycle in early mammalian embryos and its clinical implications
Lenka Radonova, Tereza Svobodova and Martin Anger
Int. J. Dev. Biol. (2019) 63: 113-122
Somatic cell nuclear transfer: failures, successes and the challenges ahead
Marta Czernik, Debora A. Anzalone, Luca Palazzese, Mami Oikawa and Pasqualino Loi
Int. J. Dev. Biol. (2019) 63: 123-130
Computational models for the dynamics of early mouse embryogenesis
Alen Tosenberger, Didier Gonze, Claire Chazaud and Geneviève Dupont
Int. J. Dev. Biol. (2019) 63: 131-142
Multiplying embryos: experimental monozygotic polyembryony in mammals and its uses
Ellen Casser, Steffen Israel and Michele Boiani
Int. J. Dev. Biol. (2019) 63: 143-155
The mammalian embryo’s first agenda: making trophectoderm
Eszter Posfai, Isidora Rovic and Andrea Jurisicova
Int. J. Dev. Biol. (2019) 63: 157-170
FGF/ERK signaling pathway: how it operates in mammalian preimplantation embryos and embryo-derived stem cells
Anna Soszyńska, Katarzyna Klimczewska and Aneta Suwińska
Int. J. Dev. Biol. (2019) 63: 171-186
Beyond the mouse: non-rodent animal models for study of early mammalian development and biomedical research
Zofia E. Madeja, Piotr Pawlak and Anna Piliszek
Int. J. Dev. Biol. (2019) 63: 187-201
Test-tube embryos - mouse and human development in vitro to blastocyst stage and beyond
Niraimathi Govindasamy, Binyamin Duethorn, Hatice O. Oezgueldez, Yung S. Kim and Ivan Bedzhov
Int. J. Dev. Biol. (2019) 63: 203-215
Assessing the epigenetic risks of assisted reproductive technologies: a way forward
Federica Zacchini, Silvestre Sampino, Adrian M. Stankiewicz, Thomas Haaf and Grazyna E. Ptak
Int. J. Dev. Biol. (2019) 63: 217-222
Diverse developmental strategies of X chromosome dosage compensation in eutherian mammals
Alexander I. Shevchenko, Elena V. Dementyeva, Irina S. Zakharova and Suren M. Zakian
Int. J. Dev. Biol. (2019) 63: 223-233
Light microscopy of mammalian gametes and embryos: methods and applications
Anna Ajduk and Maciej Szkulmowski
Int. J. Dev. Biol. (2019) 63: 235-244

Original Article

Chromatin organization and timing of polar body I extrusion identify developmentally competent mouse oocytes
Federica Cavalera, Mario Zanoni, Valeria Merico, Lucia Sacchi, Riccardo Bellazzi, Silvia Garagna and Maurizio Zuccotti
Int. J. Dev. Biol. (2019) 63: 245-251

Technical Report

Enucleolation and nucleolus transfer in mammalian oocytes and zygotes
Michal Benc, Josef Fulka, Jr., František Strejček, Martin Morovič, Matej Murín, Stanislava Martínková, Dominika Jettmarová and Jozef Laurinčík
Int. J. Dev. Biol. (2019) 63: 253-258

The International Journal of Developmental Biology
ISSN 1696-3547 (online) and 0214-6282 (print)