Vol. 63 Nos. 1/2 (2019) pp.1-72

Cover legend

The reproductive system is mostly derived from a group of embryonic cells which make up the genital disc. Both female and male sexes originate from the same cellular precursors which will give rise to genitalia and analia. The regulation of sex is what determines the development of the male or female structures, in humans, as well as in Drosophila. Size is a key characteristic of the genitalia and analia. How and by how much the genital precursors grow depends on the regulation of sex, which in turn fundamentally depends on the differential regulation of the pro-apoptotic gene hid and JNK-mediated processes which are analyzed in Arias et al. pp 17-27 in the current issue. Images on the left: longitudinal sections of the same wild type male genital disc (ventral to the top and dorsal to the bottom). Nuclei are indicated in red and analia precursor cells are labeled green. Image on the right: the adult structures that are derived from the male genital disc.


On the biomechanical properties of osteosarcoma cells and their environment
Daniel A. Müller and Unai Silvan
Int. J. Dev. Biol. (2019) 63: 1-8

Original Articles

Smed-egfr-4 is required for planarian eye regeneration
Elena Emili, Macià Esteve Pallarès, Rafael Romero and Francesc Cebrià
Int. J. Dev. Biol. (2019) 63: 9-15
Genital disc growth in Drosophila
Carolina Arias, Adriana Zapata, Francisco Ludueña-Almeida, Marcelo Zacharonok and Ana Macías
Int. J. Dev. Biol. (2019) 63: 17-27
Latrophilin2 is involved in neural crest cell migration and placode patterning in Xenopus laevis
Natsumi Yokote, Marianna Y. Suzuki-Kosaka, Tatsuo Michiue, Takahiko Hara and Kosuke Tanegashima
Int. J. Dev. Biol. (2019) 63: 29-35
Axis elongation during Xenopus tail-bud stage is regulated by GABA expressed in the anterior-to-mid neural tube
Tomoyo Furukawa, Yuki Yamasaki, Yusuke Hara, Chisa Otsuki, Hiroko Maki, Tomoyoshi Soga, Yuki Moriyama and Hiroki Kuroda
Int. J. Dev. Biol. (2019) 63: 37-43
Functional analysis of Arabidopsis and maize transgenic lines overexpressing the ADP-ribose/NADH pyrophosphohydrolase, AtNUDX7
Elizabeth Njuguna, Griet Coussens, Pia Neyt, Stijn Aesaert, Veronique Storme, Kirin Demuynck, Hannes Vanhaeren, Stijn Dhondt, Yolaine Van Haver, Linus Paul, Dirk Inzé, Hilde Nelissen and Mieke Van Lijsebettens
Int. J. Dev. Biol. (2019) 63: 45-55

Technical Article

Preparation of a fish embryo for micromanipulation: staging of development, removal of the chorion and traceability of PGCs in Prochilodus lineatus
Geovanna C.Z. Coelho, Isaac S. Yo, Tatiana M. Mira-López, Paulo S. Monzani, Dilberto R. Arashiro, Takafumi Fujimoto, José A. Senhorini and George S. Yasui
Int. J. Dev. Biol. (2019) 63: 57-65

Short Communication

Evidence for an evolutionary relationship between Vmp1 and bacterial DedA proteins
Luis-Carlos Tábara, Olivier Vincent and Ricardo Escalante
Int. J. Dev. Biol. (2019) 63: 67-71

The International Journal of Developmental Biology
ISSN 1696-3547 (online) and 0214-6282 (print)