Vol. 61 Nos. 10/11/12 (2017) pp.571-800

The Amphioxus Model System

Cover legend

The amphioxus, or lancelet, is a fish-like marine chordate which is considered to be an archetypal vertebrate form. Although specialized tunicates are closer relatives to chordates, amphioxus represents the best living outgroup proxy for the study of the evolution and development of vertebrates. It spends most of its life burrowed in the ocean floor, exposing only the front part of its body. It collects its food by filtering the surrounding water through its mouth, which is protected by conspicuous oral cirri stiffened by a cartilaginous skeleton. The illustrated amphioxus belongs to the species Branchiostoma floridae, the Florida amphioxus, which is the species that is most commonly used as a model in experimental biology. Text and photograph by Dr. David Jandzik, Department of Ecology and Evolutionary Biology, University of Colorado at Boulder (USA).


The Amphioxus Model System
Zbynek Kozmik
Int. J. Dev. Biol. (2017) 61: 571-574

Historical perspective

The ups and downs of amphioxus biology: a history
Nicholas D. Holland and Linda Z. Holland
Int. J. Dev. Biol. (2017) 61: 575-583
The dawn of amphioxus molecular biology - a personal perspective
Peter W.H. Holland
Int. J. Dev. Biol. (2017) 61: 585-590

Evolutionary insights into embryonic and adult function

Early development of amphioxus links evolutionary events with vertebrates
Kinya Yasui
Int. J. Dev. Biol. (2017) 61: 591-600
Dorsal-ventral patterning in amphioxus: current understanding, unresolved issues, and future directions
Iryna Kozmikova and Jr-Kai Yu
Int. J. Dev. Biol. (2017) 61: 601-610
Left-right asymmetry specification in amphioxus: review and prospects
Vladimir Soukup
Int. J. Dev. Biol. (2017) 61: 611-620
Metamerism in cephalochordates and the problem of the vertebrate head
Takayuki Onai, Noritaka Adachi and Shigeru Kuratani
Int. J. Dev. Biol. (2017) 61: 621-632
From so simple a beginning – what amphioxus can teach us about placode evolution
Gerhard Schlosser
Int. J. Dev. Biol. (2017) 61: 633-648
Interpreting amphioxus, and thoughts on ancestral chordate mouths and brains
Thurston Lacalli
Int. J. Dev. Biol. (2017) 61: 649-654
Origin and evolution of the chordate central nervous system: insights from amphioxus genoarchitecture
Beatriz Albuixech-Crespo, Carlos Herrera-Úbeda, Gemma Marfany, Manuel Irimia and Jordi Garcia-Fernàndez
Int. J. Dev. Biol. (2017) 61: 655-664
Amphioxus photoreceptors - insights into the evolution of vertebrate opsins, vision and circadian rhythmicity
Jiri Pergner and Zbynek Kozmik
Int. J. Dev. Biol. (2017) 61: 665-681
The long and winding path to understanding kidney structure in amphioxus - a review
Nicholas D. Holland
Int. J. Dev. Biol. (2017) 61: 683-688
Amphioxus regeneration: evolutionary and biomedical implications
Ildikó M.L. Somorjai
Int. J. Dev. Biol. (2017) 61: 689-696

Molecular level control of development and behavior

Developmental cell-cell communication pathways in the cephalochordate amphioxus: actors and functions
Stephanie Bertrand, Yann Le Petillon, Ildikó M.L. Somorjai and Hector Escriva
Int. J. Dev. Biol. (2017) 61: 697-722
Amphioxus Sp5 is a member of a conserved Specificity Protein complement and is modulated by Wnt/β-catenin signalling
Simon C. Dailey, Iryna Kozmikova and Ildikó M.L. Somorjai
Int. J. Dev. Biol. (2017) 61: 723-732
CYP26 function is required for the tissue-specific modulation of retinoic acid signaling during amphioxus development
João E. Carvalho, François Lahaye, Jenifer C. Croce and Michael Schubert
Int. J. Dev. Biol. (2017) 61: 733-747
The origin of dopaminergic systems in chordate brains: insights from amphioxus
Elisabeth Zieger, Thurston C. Lacalli, Mario Pestarino, Michael Schubert and Simona Candiani
Int. J. Dev. Biol. (2017) 61: 749-761
The opsin repertoire of the European lancelet: a window into light detection in a basal chordate
Chrysoula N. Pantzartzi, Jiri Pergner, Iryna Kozmikova and Zbynek Kozmik
Int. J. Dev. Biol. (2017) 61: 763-772

Technological advances

Keeping amphioxus in the laboratory: an update on available husbandry methods
João E. Carvalho, François Lahaye and Michael Schubert
Int. J. Dev. Biol. (2017) 61: 773-783
Characterization of an amphioxus heat-shock protein gene promoter and its application in vivo
Chaofan Xing, Guang Li, Xian Liu, Xi Deng and Yiquan Wang
Int. J. Dev. Biol. (2017) 61: 785-792
Novel polyclonal antibodies as a useful tool for expression studies in amphioxus embryos
Matteo Bozzo, Jiri Pergner, Zbynek Kozmik and Iryna Kozmikova
Int. J. Dev. Biol. (2017) 61: 793-800

The International Journal of Developmental Biology
ISSN 1696-3547 (online) and 0214-6282 (print)