Vol. 56 Nos. 6/7/8 (2012) pp.407-652

The Hydra Model System

Cover legend

The freshwater polyp Hydra has been used to study regeneration and the development of animal form for more than 250 years. Accumulating evidence suggests that all three cell lineages composing the polyp's body act like stem cell systems. Therefore, Hydra has now started to attract interest in ancestral stem cell biology. In the gastric region of the illustrated polyp and its asexual bud, interstitial stem cells and proliferating nematocyte precursors show mRNA expression of the protooncogene and stem cell maintenance factor myc1 as visualized by in situ hybridization (blue color). For more details, see the paper by Hobmayer et al., pp 509-517.

Preface

The Hydra Model System
Brigitte Galliot
Int. J. Dev. Biol. (2012) 56: 407-409

The heuristic value of the Hydra model system

Hydra, a fruitful model system for 270 years
Brigitte Galliot
Int. J. Dev. Biol. (2012) 56: 411-423
The Trembley Effect or the birth of marine zoology
Marc J. Ratcliff
Int. J. Dev. Biol. (2012) 56: 425-436
The Hydra model - a model for what?
Alfred Gierer
Int. J. Dev. Biol. (2012) 56: 437-445

Adult Developmental Biology

Modeling pattern formation in hydra: a route to understanding essential steps in development
Hans Meinhardt
Int. J. Dev. Biol. (2012) 56: 447-462
Transplantation analysis of developmental mechanisms in Hydra
Hiroshi Shimizu
Int. J. Dev. Biol. (2012) 56: 463-472
The head organizer in Hydra
Hans R. Bode
Int. J. Dev. Biol. (2012) 56: 473-478
Hydra, the everlasting embryo, confronts aging
Daniel E. Martínez and Diane Bridge
Int. J. Dev. Biol. (2012) 56: 479-487

Stem cell Biology

Interstitial stem cells in Hydra: multipotency and decision-making
Charles N. David
Int. J. Dev. Biol. (2012) 56: 489-497
Germline stem cells and sex determination in Hydra
Chiemi Nishimiya-Fujisawa and Satoru Kobayashi
Int. J. Dev. Biol. (2012) 56: 499-508
Stemness in Hydra - a current perspective
Bert Hobmayer, Marcell Jenewein, Dominik Eder, Marie-Kristin Eder, Stella Glasauer, Sabine Gufler, Markus Hartl and Willi Salvenmoser
Int. J. Dev. Biol. (2012) 56: 509-517
Hydractinia, a pioneering model for stem cell biology and reprogramming somatic cells to pluripotency
Günter Plickert, Uri Frank and Werner A. Müller
Int. J. Dev. Biol. (2012) 56: 519-534

Cell to tissue signaling

The Hydra genome: insights, puzzles and opportunities for Developmental Biologists
Robert E. Steele
Int. J. Dev. Biol. (2012) 56: 535-542
Peptide signaling in Hydra
Toshitaka Fujisawa and Eisuke Hayakawa
Int. J. Dev. Biol. (2012) 56: 543-550
Coordinated modulation of cellular signaling through ligand-gated ion channels in Hydra vulgaris (Cnidaria, Hydrozoa)
Paola Pierobon
Int. J. Dev. Biol. (2012) 56: 551-565
Components, structure, biogenesis and function of the Hydra extracellular matrix in regeneration, pattern formation and cell differentiation
Michael P. Sarras (Jr)
Int. J. Dev. Biol. (2012) 56: 567-576
The Nematocyst: a molecular map of the Cnidarian stinging organelle
Anna Beckmann and Suat Özbek
Int. J. Dev. Biol. (2012) 56: 577-582
Hydra, a model system to trace the emergence of boundaries in developing eumetazoans
Angelika Böttger and Monika Hassel
Int. J. Dev. Biol. (2012) 56: 583-591
Hydra, a versatile model to study the homeostatic and developmental functions of cell death
Silke Reiter, Marco Crescenzi, Brigitte Galliot and Wanda Buzgariu
Int. J. Dev. Biol. (2012) 56: 593-604

Ecotoxicology and environment

What Hydra can teach us about chemical ecology – how a simple, soft organism survives in a hostile aqueous environment
Tamar Rachamim and Daniel Sher
Int. J. Dev. Biol. (2012) 56: 605-611
Hydra, a model system for environmental studies
Brian Quinn, François Gagné, Christian Blaise
Int. J. Dev. Biol. (2012) 56: 613-625
Value of the Hydra model system for studying symbiosis
Goran Kovacevic
Int. J. Dev. Biol. (2012) 56: 627-635

Pedagogy

How to use Hydra as a model system to teach biology in the classroom
Patricia Bossert and Brigitte Galliot
Int. J. Dev. Biol. (2012) 56: 637-652

The International Journal of Developmental Biology
ISSN 1696-3547 (online) and 0214-6282 (print)