Vol. 55 Nos. 7/8/9 (2011) pp.665-898

Mammary Gland in Development & Cancer

Cover legend

She Lives Breast Cancer Awareness by Shelley Bain promotes breast cancer awareness and honors all women who have battled breast cancer. Shelley is a self-taught artist, who lives and works in Rockville, Maryland (USA). Through her Art, she celebrates women and the wonder that women bring to the world, by communicating her view of the amazing world of femininity, female power and the sense of pride of women. Her art expresses many aspects of the female form, from the beauty in all women, to the pain and suffering, as well as the joys and power of being a woman. Reproduced with kind permission from S. Bain. Shelley’s Art can be viewed at: www.shelley-bain.artistwebsites.com


Developmental and cancer research on the mammary gland nowadays
Marc Bracke and Olivier De Wever
Int. J. Dev. Biol. (2011) 55: 667-669

Introductory Papers

Ecosystems of invasion and metastasis in mammary morphogenesis and cancer
Marc Mareel and Susana Constantino
Int. J. Dev. Biol. (2011) 55: 671-684
The epidermal growth factor receptor/Erb-B/HER family in normal and malignant breast biology
Suzanne A. Eccles
Int. J. Dev. Biol. (2011) 55: 685-696
From the laboratory to the patient and back - an interview with Marc Mareel
Marc E. Bracke
Int. J. Dev. Biol. (2011) 55: 697-702
Four decades of discovery in breast cancer research and treatment – an interview with V. Craig Jordan
Marc Poirot
Int. J. Dev. Biol. (2011) 55: 703-712
Signaling networks in cancer - an interview with Christian Gespach
Olivier De Wever
Int. J. Dev. Biol. (2011) 55: 713-718

Mammary gland development

Mammary gland stem cells: current status and future challenges
Agla J.R. Fridriksdottir, Ole W. Petersen and Lone Rønnov-Jessen
Int. J. Dev. Biol. (2011) 55: 719-729
c-Jun N-terminal kinase activity supports multiple phases of 3D-mammary epithelial acinus formation
Sara McNally, Emmett McArdle, Emer Gilligan, Silvia Napoletano, Malgorzata Gajewska, Orla Bergin, Sarah McCarthy, Jacqueline Whyte, Alessandro Bianchi, Julianne Stack and Finian Martin
Int. J. Dev. Biol. (2011) 55: 731-744
Non-steroidal anti-inflammatory drugs target the pro-tumorigenic extracellular matrix of the postpartum mammary gland
Jenean O’Brien, Kirk Hansen, Dalit Barkan, Jeffrey Green and Pepper Schedin
Int. J. Dev. Biol. (2011) 55: 745-755
Remodeling mechanisms of the mammary gland during involution
Christine J. Watson and Peter A. Kreuzaler
Int. J. Dev. Biol. (2011) 55: 757-762
The mammary myoepithelial cell
Mejdi Moumen, Aurélie Chiche, Stéphanie Cagnet, Valérie Petit, Karine Raymond, Marisa M. Faraldo, Marie-Ange Deugnier and Marina A. Glukhova
Int. J. Dev. Biol. (2011) 55: 763-771
Connexins: a junctional crossroad to breast cancer
Jamal A. El-Saghir, Elia T. El-Habre, Marwan E. El-Sabban and Rabih S. Talhouk
Int. J. Dev. Biol. (2011) 55: 773-780
Insulin-like growth factor binding proteins and mammary gland development
Angara Sureshbabu, Elizabeth Tonner and David J. Flint
Int. J. Dev. Biol. (2011) 55: 781-789

The mammary cancer phenotype

Canine mammary tumors contain cancer stem-like cells and form spheroids with an embryonic stem cell signature
Maria Ferletta, Jan Grawé and Eva Hellmén
Int. J. Dev. Biol. (2011) 55: 791-799
Proteome changes induced by overexpression of the p75 neurotrophin receptor (p75NTR) in breast cancer cells
Jean-Philippe Wilmet, Christophe Tastet, Emilie Desruelles, Nathalie Ziental-Gelus, Vincent Blanckaert, Hubert Hondermarck and Xuefen Le Bourhis
Int. J. Dev. Biol. (2011) 55: 801-809

Cell adhesion and motility in mammary cancer

P-cadherin role in normal breast development and cancer
André Albergaria, Ana-Sofia Ribeiro, André-Filipe Vieira, Bárbara Sousa, Ana-Rita Nobre, Raquel Seruca, Fernando Schmitt and Joana Paredes
Int. J. Dev. Biol. (2011) 55: 811-822
Sialylation regulates galectin-3/ligand interplay during mammary tumour progression - a case of targeted uncloaking
Joana-Tavares de Oliveira, Augusto-José de Matos, Ana L. Santos, Rita Pinto, Joana Gomes, Venceslau Hespanhol, Roger Chammas, Aki Manninen, Emerson S. Bernardes, Celso Albuquerque Reis, Gerard Rutteman and Fátima Gärtner
Int. J. Dev. Biol. (2011) 55: 823-834
The role of non-muscle myosin IIA in aggregation and invasion of human MCF-7 breast cancer cells
Lara Derycke, Christophe Stove, Anne-Sophie Vercoutter-Edouart, Olivier De Wever, Laurent Dollé, Nathalie Colpaert, Herman Depypere, Jean-Claude Michalski and Marc Bracke
Int. J. Dev. Biol. (2011) 55: 835-840

Paracrine and endocrine regulation of mammary cancer

Role of cancer-associated fibroblasts in breast cancer development and prognosis
Abdelilah Aboussekhra
Int. J. Dev. Biol. (2011) 55: 841-849
Adipocyte is a non-trivial, dynamic partner of breast cancer cells
Jinxiang Tan, Emilie Buache, Marie-Pierre Chenard, Nassim Dali-Youcef, Marie-Christine Rio
Int. J. Dev. Biol. (2011) 55: 851-859
Tumor-associated macrophages in breast cancer: distinct subsets, distinct functions
Damya Laoui, Kiavash Movahedi, Eva Van Overmeire, Jan Van den Bossche, Elio Schouppe, Camille Mommer, Alexandros Nikolaou, Yannick Morias, Patrick De Baetselier and Jo A. Van Ginderachter
Int. J. Dev. Biol. (2011) 55: 861-867
Recent insights into the effect of natural and environmental estrogens on mammary development and carcinogenesis
Vassiliki Pelekanou and Guy Leclercq
Int. J. Dev. Biol. (2011) 55: 869-878

Mammary cancer metastasis

Exosome signaling in mammary gland development and cancer
An Hendrix and Alistair N. Hume
Int. J. Dev. Biol. (2011) 55: 879-887
The tumor macroenvironment and systemic regulation of breast cancer progression
Zafira Castaño, Kristin Tracy and Sandra S. McAllister
Int. J. Dev. Biol. (2011) 55: 889-897

The International Journal of Developmental Biology
ISSN 1696-3547 (online) and 0214-6282 (print)