Vol. 55 Nos. 4/5 (2011) pp.341-567

Angiogenesis in Development & Cancer

Cover legend

The Blood of the World (1927), oil on canvas by the surrealist Belgian artist René Magritte (1898-1967) who described his work as "visible images which conceal nothing; they evoke mystery and, indeed, when one sees one of my pictures, one asks oneself this simple question: what does that mean? It does not mean anything, because mystery means nothing either, it is unknowable". However, to the keen eye, this picture could be seen to represent the vital role of vasculogenesis for the normal development of organisms and for the pathological growth of tumors.


Angiogenesis in Development and Cancer Today
Domenico Ribatti and Valentin Djonov
Int. J. Dev. Biol. (2011) 55: 343-344

Introductory Papers

Evolution of angiogenesis
Ramón Muñoz-Chápuli
Int. J. Dev. Biol. (2011) 55: 345-351
Signal transduction in vasculogenesis and developmental angiogenesis
Sunita Patel-Hett and Patricia A. D’Amore
Int. J. Dev. Biol. (2011) 55: 353-363
The role of angiogenic growth factors in organogenesis
Enrico Crivellato
Int. J. Dev. Biol. (2011) 55: 365-375
A brief history of angiogenesis assays
Anca-Maria Cimpean, Domenico Ribatti and Marius Raica
Int. J. Dev. Biol. (2011) 55: 377-382


From the discovery of Vascular Endothelial Growth Factor to the introduction of Avastin in clinical trials - an interview with Napoleone Ferrara
Domenico Ribatti
Int. J. Dev. Biol. (2011) 55: 383-388
Fifteen years of molecular lymphangiogenesis - an interview with Kari Alitalo
Tatiana V. Petrova
Int. J. Dev. Biol. (2011) 55: 389-394
Anti-angiogenesis in cancer; met and unmet goals - an interview with Robert Kerbel
Francesco Bertolini
Int. J. Dev. Biol. (2011) 55: 395-398


Modeling of angioadaptation: insights for vascular development
Axel R. Pries, Bettina Reglin and Timothy W. Secomb
Int. J. Dev. Biol. (2011) 55: 399-405
Cell-based cardiovascular repair and regeneration in acute myocardial infarction and chronic ischemic cardiomyopathy – current status and future developments
Christian Templin, Thomas F. Lüscher and Ulf Landmesser
Int. J. Dev. Biol. (2011) 55: 407-417
The role of blood flow and microRNAs in blood vessel development
Dong Liu, Janna Krueger and Ferdinand Le Noble
Int. J. Dev. Biol. (2011) 55: 419-429
Hemangiomas - current therapeutic strategies
Peace Mabeta and Michael S. Pepper
Int. J. Dev. Biol. (2011) 55: 431-437
Nervous vascular parallels: axon guidance and beyond
Marco Arese, Guido Serini and Federico Bussolino
Int. J. Dev. Biol. (2011) 55: 439-445
Paracrine regulation of angiogenesis by different cell types in the aorta ring model
Roberto F. Nicosia, Penelope Zorzi, Giovanni Ligresti, Ann Morishita and Alfred C. Aplin
Int. J. Dev. Biol. (2011) 55: 447-453
Role of laminins in physiological and pathological angiogenesis
Patricia Simon-Assmann, Gertraud Orend, Elmina Mammadova-Bach, Caroline Spenlé and Olivier Lefebvre
Int. J. Dev. Biol. (2011) 55: 455-465
Current concepts of blood-brain barrier development
Stefan Liebner, Cathrin J. Czupalla and Hartwig Wolburg
Int. J. Dev. Biol. (2011) 55: 467-476
Cancer stem cells and angiogenesis
Yue Zhao, Qi Bao, Andrea Renner, Peter Camaj, Martin Eichhorn, Ivan Ischenko, Martin Angele, Axel Kleespies, Karl-Walter Jauch and Christiane Bruns
Int. J. Dev. Biol. (2011) 55: 477-482
Molecular mechanisms of lymphangiogenesis in development and cancer
Imke Albrecht and Gerhard Christofori
Int. J. Dev. Biol. (2011) 55: 483-494
The interplay between macrophages and angiogenesis in development, tissue injury and regeneration
Silvia Nucera, Daniela Biziato and Michele De Palma
Int. J. Dev. Biol. (2011) 55: 495-503
Zebrafish embryo, a tool to study tumor angiogenesis
Chiara Tobia, Giulia De Sena and Marco Presta
Int. J. Dev. Biol. (2011) 55: 505-509
Fibronectin and tenascin-C: accomplices in vascular morphogenesis during development and tumor growth
Ellen Van Obberghen-Schilling, Richard P. Tucker, Falk Saupe, Isabelle Gasser, Botond Cseh, Gertraud Orend
Int. J. Dev. Biol. (2011) 55: 511-525
Emerging paradigms and questions on pro-angiogenic bone marrow-derived myelomonocytic cells
Julien Laurent, Cédric Touvrey, Francesca Botta, François Kuonen and Curzio Ruegg
Int. J. Dev. Biol. (2011) 55: 527-534
Tumor blood vessel visualization
Jeannine Missbach-Guentner, Julia Hunia and Frauke Alves
Int. J. Dev. Biol. (2011) 55: 535-546
The use of the orthotopic model to validate antivascular therapies for cancer
Monica Loi, Daniela Di Paolo, Pamela Becherini, Alessia Zorzoli, Patrizia Perri, Roberta Carosio, Michele Cilli, Domenico Ribatti, Chiara Brignole, Gabriella Pagnan, Mirco Ponzoni and Fabio Pastorino
Int. J. Dev. Biol. (2011) 55: 547-555
Antiangiogenic cancer therapy: why do mouse and human patients respond in a different way to the same drug?
Yihai Cao
Int. J. Dev. Biol. (2011) 55: 557-562
Escape mechanisms after antiangiogenic treatment, or why are the tumors growing again?
Ruslan Hlushchuk, Andrew N. Makanya and Valentin Djonov
Int. J. Dev. Biol. (2011) 55: 563-567

The International Journal of Developmental Biology
ISSN 1696-3547 (online) and 0214-6282 (print)