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The International Journal of Developmental Biology

Volume 54 > Issue 6-7 (Special Issue)

Cover Vol. 54 N. 6-7

Developmental Hematopoiesis

Edited by: Charles Durand,Tierry Jaffredo and Alexander Medvinsky

Cover Legend

The beautiful drawing at the center represents a cross section through the area vasculosa of a 5 somite (embryonic day 8.5) rabbit embryo depicting a vessel formed by endothelial cells (Ed) within which primitive blood cells (pBlz) circulate. Two endothelial cells are changing their phenotype to give rise to round, hematopoietic cells (m). The endothelium is surrounded by a thin layer of cells designated as mesenchymal (x). Taken from Alexander A. Maximov (1909) Arch. Mikr. Anat. Entwickslungs. 73: 444-561. Encircling the drawing are the models elaborated upon in the present issue. Starting from the top to right: erythroid colony from mouse embryonic aorta (M. Souyri); E11.5 mouse embryo stained to reveal the vascular network (M. Souyri); Xenopus embryo, Stage 32 tail bud stage (V. Belo); zebrafish embryo (F. Giudicelli), 48hpf; Drosophila larva (F. Peronnet). Human embryo, Carnegie stage 12, 25-27 days post ovulation (H. Etchevers); avian embryo, HH15, 50-53h of development (C. Pouget). Composition: Sophie Gournet.

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Developmental Hematopoiesis - Preface

Charles Durand, Thierry Jaffredo and Alexander Medvinsky

Int. J. Dev. Biol. (2010) 54: 947-949

https://doi.org/10.1387/ijdb.103146cd

ES cells and endo-hematopoietic differentiation

Developmental hematopoiesis: historical background and perspectives. An interview with Nicole Le Douarin

Charles Durand and Thierry Jaffredo

Int. J. Dev. Biol. (2010) 54: 951-954

https://doi.org/10.1387/ijdb.103154cd

Novel roles for Notch, Wnt and Hedgehog in hematopoesis derived from human pluripotent stem cells

Chantal Cerdan and Mickie Bhatia

Int. J. Dev. Biol. (2010) 54: 955-964

https://doi.org/10.1387/ijdb.103067cc

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Challenges and strategies for generating therapeutic patient-specific hemangioblasts and hematopoietic stem cells from human pluripotent stem cells

Ann Peters, Paul W. Burridge, Marina V. Pryzhkova, Michal A. Levine,Tea-Soon Park, Christopher Roxbury, Xuan Yuan, Bruno Péault and Elias T. Zambidis

Int. J. Dev. Biol. (2010) 54: 965-990

https://doi.org/10.1387/ijdb.093043ap

Dissecting hematopoietic differentiation using the embryonic stem cell differentiation model

Tara L. Huber

Int. J. Dev. Biol. (2010) 54: 991-1002

https://doi.org/10.1387/ijdb.103065th

Sites of hematopoiesis: where do HSC and progenitors come from?

Novel methods for determining hematopoietic stem and progenitor cell emergence in the murine yolk sac

Christopher T. Lux and Mervin C. Yoder

Int. J. Dev. Biol. (2010) 54: 1003-1009

https://doi.org/10.1387/ijdb.103118cl

Primitive erythropoiesis in the mammalian embryo

James Palis, Jeffrey Malik, Kathleen E. McGrath and Paul D. Kingsley

Int. J. Dev. Biol. (2010) 54: 1011-1018

https://doi.org/10.1387/ijdb.093056jp

The origin and fate of yolk sac hematopoiesis: application of chimera analyses to developmental studies

Hiroo Ueno and Irving L. Weissman

Int. J. Dev. Biol. (2010) 54: 1019-1031

https://doi.org/10.1387/ijdb.093039hu

Primitive and definitive erythropoiesis in the yolk sac: a bird’s eye view

Guojun Sheng

Int. J. Dev. Biol. (2010) 54: 1033-1043

https://doi.org/10.1387/ijdb.103105gs

Aortic remodelling during hemogenesis: is the chicken paradigm unique?

Thierry Jaffredo, Charlotte Richard, Claire Pouget, Marie-Aimée Teillet, Karine Bollérot, Rodolphe Gautier and Cécile Drevon

Int. J. Dev. Biol. (2010) 54: 1045-1054

https://doi.org/10.1387/ijdb.103062tj

Hematopoietic stem cell activity in the Aorta-Gonad-Mesonephros region enhances after mid-day 11 of mouse development

Erin Taylor, Samir Taoudi and Alexander Medvinsky

Int. J. Dev. Biol. (2010) 54: 1055-1060

https://doi.org/10.1387/ijdb.103152et

Embryonic origin of human hematopoiesis

Manuela Tavian, Katia Biasch, Lidia Sinka, Judith Vallet and Bruno Péault

Int. J. Dev. Biol. (2010) 54: 1061-1065

https://doi.org/10.1387/ijdb.103097mt

Mpl receptor defect leads to earlier appearance of hematopoietic cells/hematopoietic stem cells in the Aorta-Gonad-Mesonephros region, with increased apoptosis

Maud Fleury, Laurence Petit-Cocault, Denis Clay and Michèle Souyri

Int. J. Dev. Biol. (2010) 54: 1067-1074

https://doi.org/10.1387/ijdb.103104mf

The quest for hematopoietic stem cells in the embryo. An interview with Françoise Dieterlen-Lièvre

Thierry Jaffredo and Charles Durand

Int. J. Dev. Biol. (2010) 54: 1075-1078

https://doi.org/10.1387/ijdb.103153tj

Allantois and placenta as developmental sources of hematopoietic stem cells

Françoise Dieterlen-Lièvre, Catherine Corbel and Josselyne Salaün

Int. J. Dev. Biol. (2010) 54: 1079-1087

https://doi.org/10.1387/ijdb.093047fd

Hematopoietic stem cell development in the placenta

Christos Gekas, Katrin E. Rhodes, Ben Van Handel, Akanksha Chhabra, Masaya Ueno and Hanna K.A. Mikkola

Int. J. Dev. Biol. (2010) 54: 1089-1098

https://doi.org/10.1387/ijdb.103070cg

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The placenta as a haematopoietic organ

Katrin Ottersbach and Elaine Dzierzak

Int. J. Dev. Biol. (2010) 54: 1099-1106

https://doi.org/10.1387/ijdb.093057ko

Genetic control of hematopoietic development in flies and vertebrates

Transcription factor interplay during Drosophila haematopoiesis

Lucas Waltzer, Vanessa Gobert, Dani Osman and Marc Haenlin

Int. J. Dev. Biol. (2010) 54: 1107-1115

https://doi.org/10.1387/ijdb.093054lw

Ontogeny of the Drosophila larval hematopoietic organ, hemocyte homeostasis and the dedicated cellular immune response to parasitism

Joanna Krzemien, Michele Crozatier and Alain Vincent

Int. J. Dev. Biol. (2010) 54: 1117-1125

https://doi.org/10.1387/ijdb.093053jk

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Hematopoietic development in the zebrafish

Elizabeth J. Paik and Leonard I. Zon

Int. J. Dev. Biol. (2010) 54: 1127-1137

https://doi.org/10.1387/ijdb.093042ep

Genetic control of hematopoietic development in Xenopus and zebrafish

Aldo Ciau-Uitz, Feng Liu and Roger Patient

Int. J. Dev. Biol. (2010) 54: 1139-1149

https://doi.org/10.1387/ijdb.093055ac

Hematopoietic stem cell emergence in the conceptus and the role of Runx1

Gemma Swiers, Marella de Bruijn and Nancy A. Speck

Int. J. Dev. Biol. (2010) 54: 1151-1163

https://doi.org/10.1387/ijdb.103106gs

Definitive human and mouse hematopoiesis originates from the embryonic endothelium: a new class of HSCs based on VE-cadherin expression

Estelle Oberlin, Bouchra El Hafny, Laurence Petit-Cocault and Michèle Souyri

Int. J. Dev. Biol. (2010) 54: 1165-1173

https://doi.org/10.1387/ijdb.103121eo

The Notch pathway in the developing hematopoietic system

Anna Bigas, Àlex Robert-Moreno and Lluís Espinosa

Int. J. Dev. Biol. (2010) 54: 1175-1188

https://doi.org/10.1387/ijdb.093049ab

The roles of BMP and IL-3 signaling pathways in the control of hematopoietic stem cells in the mouse embryo

Catherine Robin and Charles Durand

Int. J. Dev. Biol. (2010) 54: 1189-1200

https://doi.org/10.1387/ijdb.093040cr

Stem cells and gene networking

Gene regulatory networks governing haematopoietic stem cell development and identity

John E. Pimanda and Berthold Göttgens

Int. J. Dev. Biol. (2010) 54: 1201-1211

https://doi.org/10.1387/ijdb.093038jp