The International Journal of Developmental Biology

Volume 52 > Issue 1

Cover Vol. 52 N. 1

Cover Legend

Anterior and posterior regions of the embryo are defined at early stages in development. In vertebrates, this is achieved, in part, by the posteriorising influence of secreted growth factors that are members of the fibroblast growth factor (FGF) and Wnt families of proteins. The photograph illustrates a gastrulation stage chick embryo showing anteriorly-restricted expression of Shisa2 mRNA. Shisa proteins prevent the maturation and transport to the cell surface of receptors for both FGFs and Wnts. It is proposed that this mechanism serves to maintain anterior identity by rendering cells in that region unresponsive to the influence of these posteriorising signals. For further details, see the article by Hedge and Mason, pp. 81-85, in this issue.

OPEN ACCESS

In memoriam of Anne McLaren

Marilyn Renfree and Roger Short

Int. J. Dev. Biol. (2008) 52: 1-2

https://doi.org/10.1387/ijdb.072494mr

Essay

Peter Holland, homeobox genes and the developmental basis of animal diversity

Sebastian M. Shimeld

Int. J. Dev. Biol. (2008) 52: 3-7

https://doi.org/10.1387/ijdb.072394ss

Review

PBX proteins: much more than Hox cofactors

Audrey Laurent, Réjane Bihan, Francis Omilli, Stéphane Deschamps and Isabelle Pellerin

Int. J. Dev. Biol. (2008) 52: 9-20

https://doi.org/10.1387/ijdb.072304al

Original Articles

Drosophila retinal pigment cell death is regulated in a position-dependent manner by a cell memory gene

Nicolas Dos-Santos, Thomas Rubin, Fabienne Chalvet, Pierre Gandille, Frederic Cremazy, Jacqueline Leroy, E. Boissonneau and Laurent Théodore

Int. J. Dev. Biol. (2008) 52: 21-31

https://doi.org/10.1387/ijdb.072406nd

Expression dynamics of the LIM-homeobox genes, Lhx1 and Lhx9, in the diencephalon during chick development

Xiangnan Sun, Hirotomo Saitsu, Kohei Shiota and Makoto Ishibashi

Int. J. Dev. Biol. (2008) 52: 33-41

https://doi.org/10.1387/ijdb.072386xs

Spa-1 regulates the maintenance and differentiation of human embryonic stem cells

Young-Jin Lee, Hee-Young Nah, Seok-Ho Hong, Ji-Won Lee, Ilkyung Jeon, Jhang Ho Pak, Joo-Ryung Huh, Sung-Hoon Kim, Hee-Dong Chae, Byung-Moon Kang, Chul Geun Kim and Chung-Hoon Kim

Int. J. Dev. Biol. (2008) 52: 43-53

https://doi.org/10.1387/ijdb.072274yl

TTF-1/NKX2.1 up-regulates the in vivo transcription of nestin

Roberta Pelizzoli, Carlo Tacchetti, Paola Luzzi, Antonella Strangio, Grazia Bellese, Emanuela Zappia and Stefania Guazzi

Int. J. Dev. Biol. (2008) 52: 55-62

https://doi.org/10.1387/ijdb.062196rp

Perichondrial-mediated TGF-beta regulation of cartilage growth in avian long bone development

Marsha L. Crochiere, James K. Kubilus and Thomas F. Linsenmayer

Int. J. Dev. Biol. (2008) 52: 63-70

https://doi.org/10.1387/ijdb.072322mc

Embryonic heat shock reveals latent hsp90 translation in zebrafish (Danio rerio)

Michelle H. Connolly and Brian K. Hall

Int. J. Dev. Biol. (2008) 52: 71-79

https://doi.org/10.1387/ijdb.062241mc

Developmental Expression Patterns

Expression of Shisa2, a modulator of both Wnt and Fgf signaling, in the chick embryo

Thomas A. Hedge and Ivor Mason

Int. J. Dev. Biol. (2008) 52: 81-85

https://doi.org/10.1387/ijdb.072355th

Stromal-derived factor-1 (SDF-1) expression during early chick development

Rizwan Rehimi, Nargis Khalida, Faisal Yusuf, Fangping Dai, Gabriela Morosan-Puopolo and Beate Brand-Saberi

Int. J. Dev. Biol. (2008) 52: 87-92

https://doi.org/10.1387/ijdb.072374rr