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The International Journal of Developmental Biology

Volume 51 > Issue 6-7 (Special Issue)

Cover Vol. 51 N. 6-7

Ear Development

Edited by: Fernando Giraldez and Bernd Fritzsch

Cover Legend

The mammalian inner ear is the sensory organ responsible for balance and hearing. The developmental processes required for its formation are complicated. The cover illustration depicts representative stages of developing mouse inner ear, from a simple cyst stage in embryos to the mature pattern at birth, visualized by filling the cavity of the inner ears with paint. For further details, see article by Bok et al., 521-533.

OPEN ACCESS

Preface. Ear Development.

Fernando Giraldez and Bernd Fritzsch

Int. J. Dev. Biol. (2007) 51: 427-427

https://doi.org/10.1387/ijdb.072400fg

Introductory paper

The molecular biology of ear development - "Twenty years are nothing"

Fernando Giraldez and Bernd Fritzsch

Int. J. Dev. Biol. (2007) 51: 429-438

https://doi.org/10.1387/ijdb.072390fg

Interview

In pursuit of communication. An interview with Bob Ruben

Fernando Giraldez and Bernd Fritzsch

Int. J. Dev. Biol. (2007) 51: 439-445

https://doi.org/10.1387/ijdb.072379fg

Induction and otic placode specification

The preplacodal region: an ectodermal domain with multipotential progenitors that contribute to sense organs and cranial sensory ganglia

Andrea Streit

Int. J. Dev. Biol. (2007) 51: 447-461

https://doi.org/10.1387/ijdb.072327as

The first steps towards hearing: mechanisms of otic placode induction

Takahiro Ohyama, Andrew K. Groves and Kareen Martin

Int. J. Dev. Biol. (2007) 51: 463-472

https://doi.org/10.1387/ijdb.072320to

Expression and functions of FGF ligands during early otic development

Thomas Schimmang

Int. J. Dev. Biol. (2007) 51: 473-481

https://doi.org/10.1387/ijdb.072334ts

Regional patterning

Establishment of a proneural field in the inner ear

Gina Abelló and Berta Alsina

Int. J. Dev. Biol. (2007) 51: 483-493

https://doi.org/10.1387/ijdb.072343ga

Hindbrain signals in otic regionalization: walk on the wild side

Sylvie Schneider-Maunoury and Cristina Pujades

Int. J. Dev. Biol. (2007) 51: 495-506

https://doi.org/10.1387/ijdb.072345ss

Axial patterning in the developing vertebrate inner ear

Tanya T. Whitfield and Katherine L. Hammond

Int. J. Dev. Biol. (2007) 51: 507-520

https://doi.org/10.1387/ijdb.072380tw

Morphogenesis

Patterning and morphogenesis of the vertebrate inner ear

Jinwoong Bok, Weise Chang and Doris K. Wu

Int. J. Dev. Biol. (2007) 51: 521-533

https://doi.org/10.1387/ijdb.072381jb

Shaping the mammalian auditory sensory organ by the planar cell polarity pathway

Michael Kelly and Ping Chen

Int. J. Dev. Biol. (2007) 51: 535-547

https://doi.org/10.1387/ijdb.072344mk

Neurons and innervation

OPEN ACCESS

Axon guidance in the inner ear

Donna M. Fekete and Andrea M. Campero

Int. J. Dev. Biol. (2007) 51: 549-556

https://doi.org/10.1387/ijdb.072341df

A network of growth and transcription factors controls neuronal differentation and survival in the developing ear

Hortensia Sánchez-Calderón, Marta Milo, Yolanda León and Isabel Varela-Nieto

Int. J. Dev. Biol. (2007) 51: 557-570

https://doi.org/10.1387/ijdb.072373hs

Sensory epithelia

Cellular commitment and differentiation in the organ of Corti

Matthew W. Kelley

Int. J. Dev. Biol. (2007) 51: 571-583

https://doi.org/10.1387/ijdb.072388mk

Pocket proteins and cell cycle regulation in inner ear development

Sonia M.S. Rocha-Sanchez and Kirk W. Beisel

Int. J. Dev. Biol. (2007) 51: 585-595

https://doi.org/10.1387/ijdb.072387sr

Development of the hair bundle and mechanotransduction

Gowri D. Nayak, Helen S.K. Ratnayaka, Richard J. Goodyear and Guy P. Richardson

Int. J. Dev. Biol. (2007) 51: 597-608

https://doi.org/10.1387/ijdb.072392gn

Genetics of function & disease

Mouse models to study inner ear development and hereditary hearing loss

Lilach M. Friedman, Amiel A. Dror and Karen B. Avraham

Int. J. Dev. Biol. (2007) 51: 609-631

https://doi.org/10.1387/ijdb.072365lf

Ear regeneration

Hair cell regeneration in the avian auditory epithelium

Jennifer S. Stone and Douglas A. Cotanche

Int. J. Dev. Biol. (2007) 51: 633-647

https://doi.org/10.1387/ijdb.072408js

Non-sensory cells in the deafened organ of Corti: approaches for repair

Yehoash Raphael, Young-Ho Kim, Yasunori Osumi and Masahiko Izumikawa

Int. J. Dev. Biol. (2007) 51: 649-654

https://doi.org/10.1387/ijdb.072370yr

Stem cells for the replacement of inner ear neurons and hair cells

Rodrigo Martinez-Monedero and Albert S.B. Edge

Int. J. Dev. Biol. (2007) 51: 655-661

https://doi.org/10.1387/ijdb.072372rm

Development & evolution of the ear

Molecular evolution of the vertebrate mechanosensory cell and ear

Bernd Fritzsch, Kirk W. Beisel, Sarah Pauley and Garrett Soukup

Int. J. Dev. Biol. (2007) 51: 663-678

https://doi.org/10.1387/ijdb.072367bf

Development of Johnston's organ in Drosophila

Daniel F. Eberl and Grace Boekhoff-Falk

Int. J. Dev. Biol. (2007) 51: 679-687

https://doi.org/10.1387/ijdb.072364de