Vol. 51 Nos. 6/7 (2007) pp.425-688

Ear Development

Cover legend

The mammalian inner ear is the sensory organ responsible for balance and hearing. The developmental processes required for its formation are complicated. The cover illustration depicts representative stages of developing mouse inner ear, from a simple cyst stage in embryos to the mature pattern at birth, visualized by filling the cavity of the inner ears with paint. For further details, see article by Bok et al., 521-533.

Preface. Ear Development.
Fernando Giraldez and Bernd Fritzsch
Int. J. Dev. Biol. (2007) 51: 427-427

Introductory paper

The molecular biology of ear development - "Twenty years are nothing"
Fernando Giraldez and Bernd Fritzsch
Int. J. Dev. Biol. (2007) 51: 429-438

Interview

In pursuit of communication. An interview with Bob Ruben
Fernando Giraldez and Bernd Fritzsch
Int. J. Dev. Biol. (2007) 51: 439-445

Induction and otic placode specification

The preplacodal region: an ectodermal domain with multipotential progenitors that contribute to sense organs and cranial sensory ganglia
Andrea Streit
Int. J. Dev. Biol. (2007) 51: 447-461 The first steps towards hearing: mechanisms of otic placode induction
Takahiro Ohyama, Andrew K. Groves and Kareen Martin
Int. J. Dev. Biol. (2007) 51: 463-472 Expression and functions of FGF ligands during early otic development
Thomas Schimmang
Int. J. Dev. Biol. (2007) 51: 473-481

Regional patterning

Establishment of a proneural field in the inner ear
Gina Abelló and Berta Alsina
Int. J. Dev. Biol. (2007) 51: 483-493 Hindbrain signals in otic regionalization: walk on the wild side
Sylvie Schneider-Maunoury and Cristina Pujades
Int. J. Dev. Biol. (2007) 51: 495-506 Axial patterning in the developing vertebrate inner ear
Tanya T. Whitfield and Katherine L. Hammond
Int. J. Dev. Biol. (2007) 51: 507-520

Morphogenesis

Patterning and morphogenesis of the vertebrate inner ear
Jinwoong Bok, Weise Chang and Doris K. Wu
Int. J. Dev. Biol. (2007) 51: 521-533 Shaping the mammalian auditory sensory organ by the planar cell polarity pathway
Michael Kelly and Ping Chen
Int. J. Dev. Biol. (2007) 51: 535-547

Neurons and innervation

Axon guidance in the inner ear
Donna M. Fekete and Andrea M. Campero
Int. J. Dev. Biol. (2007) 51: 549-556 A network of growth and transcription factors controls neuronal differentation and survival in the developing ear
Hortensia Sánchez-Calderón, Marta Milo, Yolanda León and Isabel Varela-Nieto
Int. J. Dev. Biol. (2007) 51: 557-570

Sensory epithelia

Cellular commitment and differentiation in the organ of Corti
Matthew W. Kelley
Int. J. Dev. Biol. (2007) 51: 571-583 Pocket proteins and cell cycle regulation in inner ear development
Sonia M.S. Rocha-Sanchez and Kirk W. Beisel
Int. J. Dev. Biol. (2007) 51: 585-595 Development of the hair bundle and mechanotransduction
Gowri D. Nayak, Helen S.K. Ratnayaka, Richard J. Goodyear and Guy P. Richardson
Int. J. Dev. Biol. (2007) 51: 597-608

Genetics of function & disease

Mouse models to study inner ear development and hereditary hearing loss
Lilach M. Friedman, Amiel A. Dror and Karen B. Avraham
Int. J. Dev. Biol. (2007) 51: 609-631

Ear regeneration

Hair cell regeneration in the avian auditory epithelium
Jennifer S. Stone and Douglas A. Cotanche
Int. J. Dev. Biol. (2007) 51: 633-647 Non-sensory cells in the deafened organ of Corti: approaches for repair
Yehoash Raphael, Young-Ho Kim, Yasunori Osumi and Masahiko Izumikawa
Int. J. Dev. Biol. (2007) 51: 649-654 Stem cells for the replacement of inner ear neurons and hair cells
Rodrigo Martinez-Monedero and Albert S.B. Edge
Int. J. Dev. Biol. (2007) 51: 655-661

Development & evolution of the ear

Molecular evolution of the vertebrate mechanosensory cell and ear
Bernd Fritzsch, Kirk W. Beisel, Sarah Pauley and Garrett Soukup
Int. J. Dev. Biol. (2007) 51: 663-678 Development of Johnston's organ in Drosophila
Daniel F. Eberl and Grace Boekhoff-Falk
Int. J. Dev. Biol. (2007) 51: 679-687

The International Journal of Developmental Biology
ISSN 1696-3547 (online) and 0214-6282 (print)