Vol. 50 No. 8 (2006) pp.659-728

Cover legend

FGF (fibroblast growth factor) signalling between the limb bud mesenchyme and the apical ectodermal ridge (AER) is critical for limb patterning and growth. The AER is a specialized epithelium running around the tip of the limb bud and, as the cover picture shows, a gene encoding Flrt3 (fibronectin-leucine-rich transmembrane protein 3) is strongly expressed here and outlines the limb bud of stage HH20 chick embryos. Flrt3 has been suggested to regulate FGF signalling by physically interacting with FGF receptors and enhancing downstream signalling. For further details, see the paper by Smith et al. pp. 701-704 in the present issue.

Meeting Report

Eye development at the Houston "Fly Meeting"
Amit Singh
Int. J. Dev. Biol. (2006) 50: 659-663


Retinal ganglion cells: dying to survive
Marc B. Guerin, Declan P. McKernan, Colm J. O'Brien and Thomas G. Cotter
Int. J. Dev. Biol. (2006) 50: 665-674

Original Articles

Hox and ParaHox genes in Nemertodermatida, a basal bilaterian clade
Eva Jiménez-Guri, Jordi Paps, Jordi García-Fernández and Emili Saló
Int. J. Dev. Biol. (2006) 50: 675-679
Xtbx6r, a novel T-box gene expressed in the paraxial mesoderm, has anterior neural-inducing activity
Shigeharu Yabe, Shunsuke Tazumi, Jun Yokoyama and Hideho Uchiyama
Int. J. Dev. Biol. (2006) 50: 681-689

Technical Article

Visualization of primordial germ cells in vivo using GFP-nos1 3'UTR mRNA
Taiju Saito, Takafumi Fujimoto, Shingo Maegawa, Kunio Inoue, Minoru Tanaka, Katsutoshi Arai and Etsuro Yamaha
Int. J. Dev. Biol. (2006) 50: 691-700

Developmental Expression Patterns

The expression of Flrt3 during chick limb development
Terence G. Smith and Cheryll Tickle
Int. J. Dev. Biol. (2006) 50: 701-704
N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase expression during early mouse embryonic development
Ana-Marisa Salgueiro, Mário Filipe and José-António Belo
Int. J. Dev. Biol. (2006) 50: 705-708
Expression of Dlx5 and Dlx6 during specification of the elbow joint
Deborah Ferrari and Robert A. Kosher
Int. J. Dev. Biol. (2006) 50: 709-713

The International Journal of Developmental Biology
ISSN 1696-3547 (online) and 0214-6282 (print)