Vol. 41 No. 5 (1997) pp.643-750

October 1997

Cover legend

Axis formation in Xenopus req uires cortical rotation and mesoderm induction. In untreated embryos (left embryo in cover picture) cortical rotation shifts a dorsalizing activity towards the future dorsal side. The expression domains of nr3 and sia, which are activated via a process ass ociated with the region of the prospective mesoderm in the marginal zone. In UV-treated em bryos (right embryo) cortical rotation is blocked and dorsal-specific genes are activated in cells at the vegetal pole after MBT. Due to the lack of overlap between their expressio n domain and the marginal zone, the expression of genes such as gsc cannot be maint ained outside the mesodermal region. Under these conditions, no organizer can form and no axis can be established. For details see "Cortical rotation is required for the correct s patial expression of nr3, sia and gsc in Xenopus embryos" by M edina et al. in this issue.


Relevance of proto-oncogenes as growth modulators in organogenesis of the mammalian embryonic kidney.
A Kumar, E I Wallner, F A Carone, D G Scarpelli and Y S Kanwar
Int. J. Dev. Biol. (1997) 41: 643-653

Original articles

Homeobox genes from clusters A and B demonstrate characteristics of temporal colinearity and differential restrictions in spatial expression domains in the branching mouse lung.
R Mollard and M Dziadek
Int. J. Dev. Biol. (1997) 41: 655-666
Characterization and early embryonic expression of a neural specific transcription factor xSOX3 in Xenopus laevis.
R Penzel, R Oschwald, Y Chen, L Tacke and H Grunz
Int. J. Dev. Biol. (1997) 41: 667-677
Mouse molar morphogenesis revisited by three-dimensional reconstruction. III. Spatial distribution of mitoses and apoptoses up to bell-staged first lower molar teeth.
L Viriot, R Peterková, J L Vonesch, M Peterka, J V Ruch and H Lesot
Int. J. Dev. Biol. (1997) 41: 679-690
Isolation of cDNA clones for genes that are expressed in the tail region of the ascidian tailbud embryo.
H Takahashi, K Ishida, K W Makabe and N Satoh
Int. J. Dev. Biol. (1997) 41: 691-698
Developmental expression of H3.3A variant histone mRNA in mouse.
L A López-Fernández, D M López-Alañón, V Castañeda, D B Krimer and J del Mazo
Int. J. Dev. Biol. (1997) 41: 699-703
A 3' remote control region is a candidate to modulate Hoxb-8 expression boundaries.
I Valarché, W de Graaff and J Deschamps
Int. J. Dev. Biol. (1997) 41: 705-714
Targeted over-expression of FGF in chick embryos induces formation of ectopic neural cells.
L Rodríguez-Gallardo, V Climent, V Garciá-Martínez, G C Schoenwolf and I S Alvarez
Int. J. Dev. Biol. (1997) 41: 715-723
Distribution of BDNF and trkB mRNA in the otic region of 3.5 and 4.5 day chick embryos as revealed with a combination of in situ hybridization and tract tracing.
F Hallböök and B Fritzsch
Int. J. Dev. Biol. (1997) 41: 725-732

Short contributions

Shh, Fgf4 and Hoxd gene expression in the mouse limb mutant hypodactyly.
K E Robertson, C Tickle and S M Darling
Int. J. Dev. Biol. (1997) 41: 733-736
Contralateral efferent neurons can be detected in the hindbrain outside of rhombomere 4.
M Mallo
Int. J. Dev. Biol. (1997) 41: 737-739
Cortical rotation is required for the correct spatial expression of nr3, sia and gsc in Xenopus embryos.
A Medina, S R Wendler and H Steinbeisser
Int. J. Dev. Biol. (1997) 41: 741-745
Local origin of cells in FGF-4 - induced outgrowth of amputated chick wing bud stumps.
K Kostakopoulou, N Vargesson, J D Clarke, P M Brickell and C Tickle
Int. J. Dev. Biol. (1997) 41: 747-750

The International Journal of Developmental Biology
ISSN 1696-3547 (online) and 0214-6282 (print)