TY  - JOUR
TI  - Drosophila differentiation genes instrumental in tumor suppression.
AU  - Gateff, E
AU  - Kurzik-Dumke, U
AU  - Wismar, J
AU  - Loffler, T
AU  - Habtemichael, N
AU  - Konrad, L
AU  - Dreschers, S
AU  - Kaiser, S
AU  - Protin, U
T2  - The International Journal of Developmental Biology
AB  - Tumor suppressor genes of Drosophila are developmental genes which, in the homozygously mutated state, induce in one step malignant or benign neoplastic transformation of specific cell types. They act early in development and by this set the stage for cell specific differentiation of imaginal discs, adult optic neuroblasts, blood and gonial cells. The structure, expression and possible function of the following four tumor suppressor genes are discussed: tumorous imaginal disc, lethal (3) malignant brain tumor, lethal (3) malignant blood neoplasm-1 and benign (2) gonial cell neoplasm.
PY  - 1996
VL  - 40
IS  - 1
SP  - 149
EP  - 156
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/8735924
Y2  - 2024/05/04/00:13:53
ER  -