TY - JOUR TI - The mammalian embryo’s first agenda: making trophectoderm AU - Posfai, Eszter AU - Rovic, Isidora AU - Jurisicova, Andrea T2 - The International Journal of Developmental Biology AB - One of the bottlenecks for a successful pregnancy in mammalian species is the implantation of the early embryo into the wall of the mother’s uterus. The first cell lineage the embryo sets aside following fertilization is the trophectoderm – a specialized cell type that establishes contact with the mother and mediates embryo implantation. We summarize the events that lead to the formation of the trophectoderm lineage in the preimplantation embryo and highlight key features of this cell type, which could be useful in the clinical setting for prediction of implantation outcomes. PY - 2019 DO - 10.1387/ijdb.180404ep VL - 63 IS - 3-4-5 SP - 157 EP - 170 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/180404ep Y2 - 2024/05/01/21:30:11 ER -