TY  - JOUR
TI  - Escherichia coli-based cell-free extract development for protein-based cancer therapeutic production
AU  - Salehi, AminS. M.
AU  - Earl, ConnerC.
AU  - Muhlestein, Christina
AU  - Bundy, BradleyC.
T2  - The International Journal of Developmental Biology
AB  - Cell-free protein synthesis has been around for decades but it has never been close to becoming a robust tool for the production of biotherapeutic agents. In this review, we focus on how Escherichia coli-based cell-free protein synthesis can be modified in various ways to produce challenging, complex anticancer biotherapeutics. Here we report progress in extract preparation and its relation to cell-free cancer research. The future prospects of cell-free technology and its potential in various areas of cancer therapeutics production are also highlighted.
PY  - 2016
DO  - 10.1387/ijdb.160125bb
VL  - 60
IS  - 7-8-9
SP  - 237
EP  - 243
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/160125bb
Y2  - 2024/05/04/05:00:01
ER  -