TY  - JOUR
TI  - The genome sequence of the corn snake (<I>Pantherophis guttatus</I>), a valuable resource for EvoDevo studies in squamates
AU  - Ullate-Agote, Asier
AU  - Milinkovitch, MichelC.
AU  - Tzika, AthanasiaC.
T2  - The International Journal of Developmental Biology
AB  - Squamates (snakes and lizards) exhibit a striking variety of phenotypes, with little known on their generative mechanisms. Studies aiming to understand the genetic basis of this wide diversity in morphology, physiology and ecology will greatly benefit from whole genome sequencing initiatives, as they provide the foundation for comparative analyses and improve our understanding of the evolution, development and diversification of traits. Here, we present the first draft genome of the corn snake Pantherophis guttatus, an oviparous snake that we promote as a particularly appropriate model species for evolutionary developmental studies in squamates. We sequenced 100-base paired-end reads from multiple individuals of a single family (parents and offspring) that produced a genome assembly of 1.53 gigabases (Gb), roughly covering 75% of the expected total genome size, and 297,768 scaffolds >1 Kb. We were able to fully retrieve 86, and partially another 106, of the 248 CEGMA core genes, indicating that a high genome completeness was achieved, even though the assembly is fragmented. Using MAKER2, we annotated 10,917 genes with high confidence (Annotation Edit Distance (AED)
PY  - 2014
DO  - 10.1387/ijdb.150060at
VL  - 58
IS  - 10-11-12
SP  - 881
EP  - 888
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/150060at
Y2  - 2024/04/29/19:04:09
ER  -