TY - JOUR TI - The evolution of embryo implantation AU - McGowen, MichaelR. AU - Erez, Offer AU - Romero, Roberto AU - Wildman, DerekE. T2 - The International Journal of Developmental Biology AB - Embryo implantation varies widely in placental mammals. We review this variation in mammals with a special focus on two features: the depth of implantation and embryonic diapause. We discuss the two major types of implantation depth, superficial and interstitial, and map this character on a well-resolved molecular phylogenetic tree of placental mammals. We infer that relatively deep interstitial implantation has independently evolved at least eight times within placental mammals. Moreover, the superficial type of implantation represents the ancestral state for placental mammals. In addition, we review the genes involved in various phases of implantation, and suggest a future direction in investigating the molecular evolution of implantation-related genes. PY - 2014 DO - 10.1387/ijdb.140020dw VL - 58 IS - 2-3-4 SP - 155 EP - 161 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/140020dw Y2 - 2024/04/28/21:21:07 ER -