TY - JOUR TI - C/EBP and c-JUN proteins activate the proximal enhancer of the developmentally regulated alpha-fetoprotein gene. AU - Houart, C AU - Szpirer, J AU - Szpirer, C T2 - The International Journal of Developmental Biology AB - The expression of the alpha-fetoprotein (AFP) gene is developmentally regulated. Active transcription of this gene depends on a proximal enhancer sequence located between positions D-203 bp and -81 bp, upstream the initiation site. This enhancer contains several putative binding sites for transcription factors. By transfection experiments, we showed that the enhancer activity can be driven by interactions with two regulatory factors, namely C/EBP and c-JUN. PY - 1992 VL - 36 IS - 1 SP - 109 EP - 114 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/1378295 Y2 - 2024/04/29/05:54:10 ER -