TY - JOUR TI - Transformation of the mitochondrial genome AU - Larosa, VĂ©ronique AU - Remacle, Claire T2 - The International Journal of Developmental Biology AB - Although mitochondrial transformation is highly desirable in mammals and plants, it is only possible in two unicellular organisms, the budding yeast Saccharomyces cerevisiae and the unicellular green alga Chlamydomonas reinhardtii. Here, we give an overview of the attempts made to transform mitochondria of mammals and plants and the possible reasons for their failure. This review briefly describes the mitochondrial transformation principles in yeast and describes in more detail the transformation and its applications in Chlamydomonas. PY - 2013 DO - 10.1387/ijdb.130230cr VL - 57 IS - 6-7-8 SP - 659 EP - 665 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/130230cr Y2 - 2024/05/06/00:41:18 ER -