TY  - JOUR
TI  - Aminopeptidase activity levels during axonal and dendritic growth in the rat brain.
AU  - de Gandarias, J M
AU  - Irazusta, J
AU  - Echevarria, E
AU  - San Martin, E
AU  - Casis, L
T2  - The International Journal of Developmental Biology
AB  - Brain aminopeptidase activity has been suggested as a candidate for the regulation and biotransformation of several neuropeptides. In this paper, changes in Lys- and Leu-aminopeptidase activities in rat brain hemispheres, cerebellum and medulla were examined in 1-, 3-, 5- and 7-days postnatal subjects. Aminopeptidase activities were studied by measuring the rate of hydrolysis of the artificial chromogenic substrates Lys- and Leu-2-naphthylamides (fluorimetrically detected in triplicate). Both enzyme activities show a decrease on the 3rd day of life followed by increases on the 5th and 7th day postbirth. It is suggested that these activities could play a part in the neurochemical changes that take place during axonal and dendritic growth in the rat brain.
PY  - 1992
VL  - 36
IS  - 4
SP  - 583
EP  - 585
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/1295569
Y2  - 2024/05/07/04:10:13
ER  -