TY - JOUR TI - The color purple: analyzing alkaline phosphatase expression in experimentally manipulated sea urchin embryos in an undergraduate developmental biology course. AU - Drawbridge, Julie T2 - The International Journal of Developmental Biology AB - In these laboratory exercises, developed for a sophomore/junior-level undergraduate course in Developmental Biology, students explore the processes of differentiation and morphogenesis in sea urchin embryos by monitoring the spatio-temporal expression pattern of the endoderm marker, alkaline phosphatase. Once students have determined the normal alkaline phosphatase expression pattern, they are asked to treat sea urchin embryos in some way that perturbs normal morphogenesis. Their task is to discover whether the chosen treatment perturbs both morphogenesis and differentiation of the gut or only morphogenesis. The ease with which sea urchin embryos can be cultured and manipulated provide the Developmental Biology instructor with a powerful system for inviting students to explore questions regarding differentiation and morphogenesis. PY - 2003 VL - 47 IS - 2-3 SP - 161 EP - 164 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/12705664 Y2 - 2024/05/03/06:46:26 ER -