TY - JOUR TI - PAX genes in development and disease: the role of PAX2 in urogenital tract development. AU - Eccles, Michael R AU - He, Shujie AU - Legge, Michael AU - Kumar, Rajiv AU - Fox, Jody AU - Zhou, Chaoming AU - French, Michelle AU - Tsai, Robert W S T2 - The International Journal of Developmental Biology AB - PAX genes play an important role in fetal development. Moreover, heterozygous mutations in several PAX genes cause human disease. Here we review the role of PAX2 in kidney development, focusing on the morphological effects of PAX2 mutations. We discuss the role of PAX2 in the context of an inhibitory field model of kidney branching morphogenesis and summarize recent progress in this area. PY - 2002 VL - 46 IS - 4 SP - 535 EP - 544 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/12141441 Y2 - 2024/04/28/08:05:05 ER -