TY  - JOUR
TI  - The structure and function of vertebrate fibroblast growth factor receptor 1.
AU  - Groth, Casper
AU  - Lardelli, Michael
T2  - The International Journal of Developmental Biology
AB  - The vertebrate fibroblast growth factor receptor 1 (FGFR1) is alternatively spliced generating multiple splice variants that are differentially expressed during embryo development and in the adult body. The restricted expression patterns of FGFR1 isoforms, together with differential expression and binding of specific ligands, leads to activation of common FGFR1 signal transduction pathways, but may result in distinctively different biological responses as a result of differences in cellular context. FGFR1 isoforms are also present in the nucleus in complex with various fibroblast growth factors where they function to regulate transcription of target genes.
PY  - 2002
VL  - 46
IS  - 4
SP  - 393
EP  - 400
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/12141425
Y2  - 2024/04/29/07:10:01
ER  -