TY  - JOUR
TI  - Germes</I> is involved in translocation of germ plasm during development of <I>Xenopus</I> primordial germ cells
AU  - Yamaguchi, Takeshi
AU  - Taguchi, Ayaka
AU  - Watanabe, Kenji
AU  - Orii, Hidefumi
T2  - The International Journal of Developmental Biology
AB  - Germes mRNA and protein are components of the germ plasm in Xenopus laevis. Previously, based on phenotypic observations of tailbud embryos expressing intact and mutant Germes, it was suggested that Germes is involved in the organization of germ plasm (Berekelya et al., 2007). Recently, to observe the germ plasm in a living embryo, we generated transgenic Xenopus expressing EGFP fused with a mitochondrial targeting signal, because germ plasm is enriched with mitochondria (Taguchi et al., 2012). Using this transgenic Xenopus, we demonstrate that Germes plays an essential role in the translocation of germ plasm from the cortex to the perinuclear region in primordial germ cells during early gastrulation.
PY  - 2013
DO  - 10.1387/ijdb.120215ty
VL  - 57
IS  - 5
SP  - 439
EP  - 443
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/120215ty
Y2  - 2024/05/05/17:00:37
ER  -