TY - JOUR TI - The neural inductive response of competent chick ectoblast decreases away from the host axis and correlates with an increased proliferative activity. AU - Deshmukh, S AU - Sonawane, M AU - Modak, S P T2 - The International Journal of Developmental Biology AB - We have assessed the quality and quantity of the neural inductive response of the chick gastrula ectoblast located at increasing distancefrom the host axis. In a stage 4 gastrula, entire ectoblast exhibits neural competence. The quality of induced neural tissue shifts from deuterencephalic type in the area pellucida to archencephalic type in the area opaca and primitive medullary or palisade type atthe margin of overgrowth with a concomitant reduction in the number of induced neural cells. In contrast, the mitotic and 3H-TdR labelling frequencies in the competent ectoblast increase with increasing distance from the host axis and in a proportion inverse to the amount of induced neural tissue. It is suggested that the strong neural inductive response is correlated with low proliferative activity, or longer cell cycle time, of the competent ectoblast. PY - 2001 VL - 45 IS - 5-6 SP - 759 EP - 766 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/11669378 Y2 - 2024/04/30/00:17:48 ER -