TY  - JOUR
TI  - Differential regulation of Dlx gene expression by a BMP morphogenetic gradient.
AU  - Luo, T
AU  - Matsuo-Takasaki, M
AU  - Lim, J H
AU  - Sargent, T D
T2  - The International Journal of Developmental Biology
AB  - Three members of the vertebrate Distal-less gene family, Dlx3, 5 and 6, are transcribed in early gastrula embryos of Xenopus laevis. This expression is confined to ectoderm and is excluded from the presumptive neural plate region. Expression of all three genes is dependent upon BMP signaling, with significant differences in how the three genes respond to the BMP antagonist chordin. This correlates with the different expression domain boundaries in vivo for Dlx3 compared to Dlx5 and 6, suggesting that BMP signal attenuation could be the primary factor in determining these different patterns in the gastrula ectoderm.
PY  - 2001
VL  - 45
IS  - 4
SP  - 681
EP  - 684
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/11461005
Y2  - 2024/05/04/06:06:24
ER  -