TY  - JOUR
TI  - Expression of <I>Sox</I> family genes in early lamprey development
AU  - Uy, BenjaminR.
AU  - Simoes-Costa, Marcos
AU  - Sauka-Spengler, Tatjana
AU  - Bronner, MarianneE.
T2  - The International Journal of Developmental Biology
AB  - Members of the Sox (Sry-related high mobility group box) family of transcription factors play a variety of roles during development of both vertebrates and invertebrates. A marked expansion in gene number occurred during the emergence of vertebrates, apparently via gene duplication events that are thought to have facilitated new functions. By screening a macroarrayed library as well as the lamprey genome, we have isolated genes of the Sox B, D, E and F subfamilies in the basal jawless vertebrate, lamprey.  The expression patterns of all identified Sox genes were examined from gastrulation through early organogenesis (embryonic day 4-14), with particular emphasis on the neural crest, a vertebrate innovation. Coupled with phylogenetic analysis of these Sox genes, the results provide insight into gene duplication and di-vergence in paralog deployment occurring during early vertebrate evolution.
PY  - 2012
DO  - 10.1387/ijdb.113416bu
VL  - 56
IS  - 5
SP  - 377
EP  - 383
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/113416bu
Y2  - 2024/05/02/01:22:55
ER  -