TY - JOUR TI - Remodeling mechanisms of the mammary gland during involution AU - Watson, ChristineJ. AU - Kreuzaler, PeterA. T2 - The International Journal of Developmental Biology AB - The process of post-lactational regression, or involution, of the mammary gland is a complex event characterised by extensive death of the secretory epithelium coupled with remodelling of the extracellular matrix and adipogenesis to regenerate the fat pad. Associated with these events is an inflammatory cascade and acute phase response. The critical signalling pathways that regulated involution have been defined and a wide variety of genes have been shown to modulate the various processes involved, including cell death, phagocytosis, tissue remodelling and innate immune response. PY - 2011 DO - 10.1387/ijdb.113414cw VL - 55 IS - 7-8-9 SP - 757 EP - 762 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/113414cw Y2 - 2024/05/04/06:50:03 ER -