TY  - JOUR
TI  - Roles of Sox factors in neural determination: conserved signaling in evolution?
AU  - Sasai, Y
T2  - The International Journal of Developmental Biology
AB  - Neural differentiation in amphibian embryos is initiated by the neural inducers emanating from the Spemann-Mangold organizer. The fate of uncommitted ectoderm is determined by graded BMP activity along the dorsal-ventral axis. Several transcriptional regulators acting in early neural differentiation have been identified, including Sox, Zic, Pou, HLH and Fox factors. In this paper, I review recent molecular studies on neural determination, focusing mainly on Sox factors. I also discuss the possible conservation of regulatory factors in neural differentiation, comparing Xenopus and Drosophila counterparts.
PY  - 2001
VL  - 45
IS  - 1
SP  - 321
EP  - 326
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/11291862
Y2  - 2024/04/29/19:04:34
ER  -