TY - JOUR TI - Differential expression of two skeletal muscle beta-tropomyosin mRNAs during Xenopus laevis development. AU - Gaillard, C AU - Lerivray, H AU - Theze, N AU - Cooper, B AU - Lepetit, D AU - Mohun, T AU - Thiebaud, P T2 - The International Journal of Developmental Biology AB - A cDNA clone for a Xenopus laevis skeletal muscle beta-tropomyosin (beta-TMad) isoform was isolated from an adult skeletal muscle cDNA library. Sequence analysis revealed that this clone corresponded to a second beta-tropomyosin mRNA distinct from the one that was previously characterized (beta-TMemb). The two skeletal beta-TM mRNAs originate from distinct genes and are differentially expressed during development. Beta-TMemb mRNA is expressed only in the somites of the early embryo while beta-TMad mRNA is expressed in pre-metamorphic tadpoles and adult skeletal muscles. We have isolated the promoter region of the beta-TMemb gene and shown that a DNA construct containing 2.9 kb of promoter region is properly expressed after injection in the embryo. PY - 1999 VL - 43 IS - 2 SP - 175 EP - 178 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/10235394 Y2 - 2024/05/03/07:37:04 ER -