TY - JOUR TI - Sperm penetration through cumulus mass and zona pellucida AU - Kim, Ekyune AU - Yamashita, Misuzu AU - Kimura, Masanori AU - Honda, Arata AU - Kashiwabara, Shin-ichi AU - Baba, Tadashi T2 - The International Journal of Developmental Biology AB - Mammalian fertilization requires sperm to penetrate the cumulus mass and egg zona pellucida prior to fusion with the egg. Although sperm penetration through these physical barriers is essential, the molecular mechanism has not yet been completely elucidated. In addition to sperm motility, hyaluronan-hydrolyzing and proteolytic enzymes of sperm have been suggested to participate in the penetration events. Here we focus on the functional roles of hyaluronidase and protease in sperm passage through the cumulus mass and zona pellucida. PY - 2008 DO - 10.1387/ijdb.072528ek VL - 52 IS - 5-6 SP - 677 EP - 682 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/072528ek Y2 - 2024/05/03/00:14:17 ER -