TY - JOUR TI - Aard is specifically up-regulated in Sertoli cells during mouse testis differentiation AU - Svingen, Terje AU - Beverdam, Annemiek AU - Verma, Pali AU - Wilhelm, Dagmar AU - Koopman, Peter T2 - The International Journal of Developmental Biology AB - Aard (alanine and arginine rich domain) is a gene of unknown function, previously reported to show sexually dimorphic expression in fetal mouse gonads. Here we describe the spatio-temporal expression profile of Aard during gonad development. The period of elevated mRNA expression coincides with early differentiation of the testis and is limited to Sertoli cells of the developing testis cords. Although low levels of Aard transcripts were detected in other tissues by quantitative RT-PCR assays, high levels of Aard expression is specific to the testis in both embryonic and adult mice. PY - 2007 DO - 10.1387/ijdb.062219ts VL - 51 IS - 3 SP - 255 EP - 258 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/062219ts Y2 - 2024/05/06/18:26:27 ER -