TY  - JOUR
TI  - Common mechanisms for boundary formation in somitogenesis and brain development: shaping the 'chic' chick
AU  - Takahashi, Yoshiko
T2  - The International Journal of Developmental Biology
AB  - When organs and tissues acquire their characteristic shapes and functions during early development, boundaries are established that distinguish between and delimit distinct areas. Such boundaries are not mere edges, but also play important roles as secondary signaling centers in subsequent morphogenesis. Following on pioneering findings provided by studies in Drosophila, the mechanisms underlying boundary formation in vertebrate embryogenesis have attracted the interest of an increasing number of researchers. Somitogenesis and brain development, in particular, serve as model systems for the study of the molecular and cellular events occurring at developing boundaries. Recent findings allow us to draw some general pictures concerning the shared mechanisms that participate in these processes of organogenesis, in which Notch, Eph/ephrin and cadherin-mediated signaling are among the main key regulators.
PY  - 2005
DO  - 10.1387/ijdb.041960yt
VL  - 49
IS  - 2-3
SP  - 221
EP  - 230
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/041960yt
Y2  - 2024/04/27/23:51:15
ER  -